Pharmaceutical Statistics, Fifth Edition / Фармацевтическая статистика, 5-е издание
Год издания: 2009
Автор: Sanford Bolton, Charles Bon / Сэнфорд Болтон, Чарльз Бон
Жанр или тематика: Математика, фармацевтика
Издательство: Informa Healthcare USA, Inc.
ISBN: 978-1-4200-7422-2
Серия: Drugs and the Pharmaceutical Sciences
Язык: Английский
Формат: PDF
Качество: Издательский макет или текст (eBook)
Интерактивное оглавление: Да
Количество страниц: 674
Описание
Предлагая примеры и решения практического характера, книга является наиболее полным и детальным руководством по различным приложениям статистики к исследованиям в области фармацевтической индустрии, включая клинические эксперименты и оценку биоэквивалентности.
Description
Through the use of practical examples and solutions, Pharmaceutical Statistics: Practical and Clinical Applications, Fifth Edition provides the most complete and comprehensive guide to the various statistical applications and research issues in the pharmaceutical industry, particularly in clinical trials and bioequivalence studies.
* Includes step-by-step examples for analyzing text examples using common software programs
* Covers the in vitro-in vivo correlation, and how it can be used in the drug development process to improve FDA acceptance of post-approval manufacturing changes
* Discusses adaptive designs in clinical research and advanced statistical designs in clinical trials with safety/efficacy endpoints
* Explains one- and two-sided statistical tests
* Covers interim and sequential analysis for clinical trials and bioequivalence studies
* Discusses assumptions and applications of nonparametric methods
* Includes the application of confidence intervals for a ratio based on Fieller’s Theorem
* Expands on the concepts of multiple and logistic regression
* Provides tables in the appendix to clarify material
